PTGER2 Overexpression in Colorectal Cancer is Associated with Microsatellite Instability, Independent of CpG Island Methylator Phenotype

BACKGROUND: Prostaglandin-endoperoxide synthase 2 (PTGS2, the HUGO Gene Nomenclature Committee-approved official symbol for cycloxygenase-2, COX-2) and its enzymatic product prostaglandin E2 have critical roles in inflammation and carcinogenesis through the G-protein-coupled prostaglandin E receptor...

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Detalhes bibliográficos
Main Authors: Baba, Yoshifumi, Nosho, Katsuhiko, Shima, Kaori, Goessling, Wolfram, Chan, Andrew T., Ng, Kimmie, Chan, Jennifer A., Giovannucci, Edward L., Fuchs, Charles S., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837535/
https://ncbi.nlm.nih.gov/pubmed/20200425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-1154
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