Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element

Analysis of synonymous mutations established that although the primary amino acid sequence remains unchanged, alterations in transcription and translation can result in significant phenotypic consequences. We report the novel observation that a series of nonsynonymous mutations in an unconserved str...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Rahman, Hadiar, Rudrow, Andrew, Carneglia, Joshua, Joly, Sister Stephen Patrick, Nicotera, Dante, Naldrett, Michael, Choy, John, Ambudkar, Suresh V., Golin, John
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945031/
https://ncbi.nlm.nih.gov/pubmed/31757931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400863
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