Deubiquitinating enzyme USP10 promotes hepatocellular carcinoma metastasis through deubiquitinating and stabilizing Smad4 protein

Hepatocellular carcinoma (HCC) has emerged as one of the most prevalent life‐threatening cancers, and the high mortality rate is largely due to the metastasis. The sustained activation of Smad4 and transforming growth factor‐β (TGF‐β) is closely associated with advanced HCC metastasis. However, the...

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Publicat a:Mol Oncol
Autors principals: Yuan, Tao, Chen, Zibo, Yan, Fangjie, Qian, Meijia, Luo, Hong, Ye, Song, Cao, Ji, Ying, Meidan, Dai, Xiaoyang, Gai, Renhua, Yang, Bo, He, Qiaojun, Zhu, Hong
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944132/
https://ncbi.nlm.nih.gov/pubmed/31721429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12596
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