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Deubiquitinating enzyme USP10 promotes hepatocellular carcinoma metastasis through deubiquitinating and stabilizing Smad4 protein

Hepatocellular carcinoma (HCC) has emerged as one of the most prevalent life‐threatening cancers, and the high mortality rate is largely due to the metastasis. The sustained activation of Smad4 and transforming growth factor‐β (TGF‐β) is closely associated with advanced HCC metastasis. However, the...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Yuan, Tao, Chen, Zibo, Yan, Fangjie, Qian, Meijia, Luo, Hong, Ye, Song, Cao, Ji, Ying, Meidan, Dai, Xiaoyang, Gai, Renhua, Yang, Bo, He, Qiaojun, Zhu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944132/
https://ncbi.nlm.nih.gov/pubmed/31721429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12596
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