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USP26 regulates TGF‐β signaling by deubiquitinating and stabilizing SMAD7
The amplitude of transforming growth factor‐β (TGF‐β) signal is tightly regulated to ensure appropriate physiological responses. As part of negative feedback loop SMAD7, a direct transcriptional target of downstream TGF‐β signaling acts as a scaffold to recruit the E3 ligase SMURF2 to target the TGF...
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| Publicado en: | EMBO Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5412796/ https://ncbi.nlm.nih.gov/pubmed/28381482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643270 |
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