Are the Hydantoin-1,3,5-triazine 5-HT(6)R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro

Though the 5-HT(6) serotonin receptor is an important target giving both agonists and antagonists similar therapeutic potency in the treatment of topic CNS-diseases, no 5-HT(6)R ligand has reached the pharmaceutical market yet due to the too narrow chemical space of the known 5-HT(6)R agents and ins...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lubelska, Annamaria, Latacz, Gniewomir, Jastrzębska-Więsek, Magdalena, Kotańska, Magdalena, Kurczab, Rafał, Partyka, Anna, Marć, Małgorzata Anna, Wilczyńska, Daria, Doroz-Płonka, Agata, Łażewska, Dorota, Wesołowska, Anna, Kieć-Kononowicz, Katarzyna, Handzlik, Jadwiga
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943527/
https://ncbi.nlm.nih.gov/pubmed/31817628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244472
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados