Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT(6) Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo

This study focuses on the design, synthesis, biological evaluation, and computer-aided structure-activity relationship (SAR) analysis for a novel group of aromatic triazine-methylpiperazines, with an hydantoin spacer between 1,3,5-traizine and the aromatic fragment. New compounds were synthesized an...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Molecules
Главные авторы: Kurczab, Rafał, Ali, Wesam, Łażewska, Dorota, Kotańska, Magdalena, Jastrzębska-Więsek, Magdalena, Satała, Grzegorz, Więcek, Małgorzata, Lubelska, Annamaria, Latacz, Gniewomir, Partyka, Anna, Starek, Małgorzata, Dąbrowska, Monika, Wesołowska, Anna, Jacob, Claus, Kieć-Kononowicz, Katarzyna, Handzlik, Jadwiga
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222450/
https://ncbi.nlm.nih.gov/pubmed/30282913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102529
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы