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SIVcpz cross-species transmission and viral evolution towards HIV-1 in a humanized mouse model
HIV-1 evolved from its progenitor SIV strains, but details are lacking on its adaptation to the human host. We followed the evolution of SIVcpz in humanized mice to mimic cross-species transmission. Increasing viral loads, CD4(+) T-cell decline, and non-synonymous mutations were seen in the entire g...
Tallennettuna:
| Julkaisussa: | J Med Primatol |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942238/ https://ncbi.nlm.nih.gov/pubmed/31576587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jmp.12440 |
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