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Glutathione facilitates enterovirus assembly by binding at a druggable pocket

Enteroviruses cause a range of human and animal diseases, some life-threatening, but there remain no licenced anti-enterovirus drugs. However, a benzene-sulfonamide derivative and related compounds have been shown recently to block infection of a range of enteroviruses by binding the capsid at a pos...

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Publicat a:Commun Biol
Autors principals: Duyvesteyn, Helen M. E., Ren, Jingshan, Walter, Thomas S., Fry, Elizabeth E., Stuart, David I.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941975/
https://ncbi.nlm.nih.gov/pubmed/31909201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0722-x
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