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The Impact of p53 on Aristolochic Acid I-Induced Gene Expression In Vivo
Exposure to aristolochic acid (AA) is linked to kidney disease and urothelial cancer in humans. The major carcinogenic component of the AA plant extract is aristolochic acid I (AAI). The tumour suppressor p53 is frequently mutated in AA-induced tumours. We previously showed that p53 protects from AA...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6940885/ https://ncbi.nlm.nih.gov/pubmed/31817608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246155 |
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