Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

Lineage-defining transcription factors (TFs) are compelling targets for leukemia therapy, yet they are among the most challenging proteins to modulate directly with small molecules. We previously used CRISPR screening to identify a salt-inducible kinase 3 (SIK3) requirement for the growth of acute m...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Blood
Main Authors: Tarumoto, Yusuke, Lin, Shan, Wang, Jinhua, Milazzo, Joseph P., Xu, Yali, Lu, Bin, Yang, Zhaolin, Wei, Yiliang, Polyanskaya, Sofya, Wunderlich, Mark, Gray, Nathanael S., Stegmaier, Kimberly, Vakoc, Christopher R.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2020
Teme:
Myeloid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940199/
https://ncbi.nlm.nih.gov/pubmed/31697837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001576
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki