Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer’s disease patient brain samples

Identification of multiple immune-related genetic risk factors for sporadic AD (sAD) have put the immune system center stage in mechanisms underlying this disorder. Comprehensive analysis of microglia in different stages of AD in human brains revealed microglia activation to follow the progression o...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol
Autors principals: Prokop, Stefan, Miller, Kelly R., Labra, Sergio R., Pitkin, Rose M., Hoxha, Kevt’her, Narasimhan, Sneha, Changolkar, Lakshmi, Rosenbloom, Alyssa, Lee, Virginia M.-Y., Trojanowski, John Q.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939638/
https://ncbi.nlm.nih.gov/pubmed/31350575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02048-2
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