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RanGTP and importin β regulate meiosis I spindle assembly and function in mouse oocytes

Homologous chromosome segregation during meiosis I (MI) in mammalian oocytes is carried out by the acentrosomal MI spindles. Whereas studies in human oocytes identified Ran GTPase as a crucial regulator of the MI spindle function, experiments in mouse oocytes questioned the generality of this notion...

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Bibliographic Details
Published in:EMBO J
Main Authors: Drutovic, David, Duan, Xing, Li, Rong, Kalab, Petr, Solc, Petr
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939199/
https://ncbi.nlm.nih.gov/pubmed/31617608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101689
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