Spindle Assembly in the Absence of a RanGTP Gradient Requires Localized CPC Activity

During animal cell division, a gradient of GTP-bound Ran is generated around mitotic chromatin [1, 2]. It is generally accepted that this RanGTP gradient is essential for organizing the spindle since it locally activates critical spindle assembly factors [3–5]. Here, we show in Xenopus egg extract,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Maresca, Thomas J., Groen, Aaron C., Gatlin, Jesse C., Ohi, Ryoma, Mitchison, Timothy J., Salmon, Edward D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752711/
https://ncbi.nlm.nih.gov/pubmed/19540121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.05.061
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia