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The RanGTP gradient – a GPS for the mitotic spindle

The GTPase Ran has a key role in nuclear import and export, mitotic spindle assembly and nuclear envelope formation. The cycling of Ran between its GTP- and GDP-bound forms is catalyzed by the chromatin-bound guanine nucleotide exchange factor RCC1 and the cytoplasmic Ran GTPase-activating protein R...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Kalab, Petr, Heald, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185306/
https://ncbi.nlm.nih.gov/pubmed/18469014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.005959
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