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The RanGTP gradient – a GPS for the mitotic spindle
The GTPase Ran has a key role in nuclear import and export, mitotic spindle assembly and nuclear envelope formation. The cycling of Ran between its GTP- and GDP-bound forms is catalyzed by the chromatin-bound guanine nucleotide exchange factor RCC1 and the cytoplasmic Ran GTPase-activating protein R...
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| Опубликовано в: : | J Cell Sci |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185306/ https://ncbi.nlm.nih.gov/pubmed/18469014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.005959 |
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