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The RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and Beyond

The small GTPase Ran regulates the interaction of transport receptors with a number of cellular cargo proteins. The high affinity binding of the GTP-bound form of Ran to import receptors promotes cargo release, whereas its binding to export receptors stabilizes their interaction with the cargo. This...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Cavazza, Tommaso, Vernos, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707252/
https://ncbi.nlm.nih.gov/pubmed/26793706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2015.00082
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