RanGTP induces an effector gradient of XCTK2 and importin α/β for spindle microtubule cross-linking

High RanGTP around chromatin is important for governing spindle assembly during meiosis and mitosis by releasing the inhibitory effects of importin α/β. Here we examine how the Ran gradient regulates Kinesin-14 function to control spindle organization. We show that Xenopus Kinesin-14, XCTK2, and imp...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Ems-McClung, Stephanie C., Emch, Mackenzie, Zhang, Stephanie, Mahnoor, Serena, Weaver, Lesley N., Walczak, Claire E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041689/
https://ncbi.nlm.nih.gov/pubmed/31865374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201906045
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge