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Soluble Guanylate Cyclase Agonists Induce Bronchodilation in Human Small Airways

The soluble guanylyl cyclase (sGC)–cyclic guanosine monophosphate signaling pathway evokes vascular smooth muscle relaxation; whether this pathway mediates airway smooth muscle relaxation remains controversial. We posit that sGC activators are equi-effective as β-agonists in reversing contractile ag...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Koziol-White, Cynthia J., Ghosh, Arnab, Sandner, Peter, Erzurum, Serpil E., Stuehr, Dennis J., Panettieri, Reynold A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938135/
https://ncbi.nlm.nih.gov/pubmed/31340135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0001OC
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