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Maturation, inactivation, and recovery mechanisms of soluble guanylyl cyclase

Soluble guanylate cyclase (sGC) is a heme-containing heterodimeric enzyme that generates many molecules of cGMP in response to its ligand nitric oxide (NO); sGC thereby acts as an amplifier in NO-driven biological signaling cascades. Because sGC helps regulate the cardiovascular, neuronal, and gastr...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Stuehr, Dennis J., Misra, Saurav, Dai, Yue, Ghosh, Arnab
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949132/
https://ncbi.nlm.nih.gov/pubmed/33508317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100336
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