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Myoglobin maturation is driven by the hsp90 chaperone machinery and by soluble guanylyl cyclase
Myoglobin (Mb) maturation involves heme incorporation as a final step. We investigated a role for heat shock protein (hsp) 90 in Mb maturation in C2C12 skeletal muscle myoblasts and cell lines. We found the following: 1) Hsp90 directly interacts preferentially with heme-free Mb both in purified form...
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| Veröffentlicht in: | FASEB J |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Federation of American Societies for Experimental Biology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6704453/ https://ncbi.nlm.nih.gov/pubmed/31170354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802793RR |
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