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Measuring the Stoichiometry of Antimicrobial Peptides in Nanodiscs with Native Mass Spectrometry

Antimicrobial peptides (AMPs) and other membrane active compounds attack pathogens by targeting the lipid bilayer rather than specific proteins, which may have advantages in combating drug resistance. However, the mechanisms of AMP toxicity and selectivity are poorly understood due to challenges in...

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Bibliographische Detailangaben
Veröffentlicht in:J Biomol Tech
Hauptverfasser: Marty, Michael, Walker, Lawrence, Marzluff, Elaine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association of Biomolecular Resource Facilities 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938118/
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