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Measuring the Stoichiometry of Antimicrobial Peptides in Nanodiscs with Native Mass Spectrometry

Antimicrobial peptides (AMPs) and other membrane active compounds attack pathogens by targeting the lipid bilayer rather than specific proteins, which may have advantages in combating drug resistance. However, the mechanisms of AMP toxicity and selectivity are poorly understood due to challenges in...

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Publicado en:J Biomol Tech
Autores principales: Marty, Michael, Walker, Lawrence, Marzluff, Elaine
Formato: Artigo
Lenguaje:Inglês
Publicado: Association of Biomolecular Resource Facilities 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938118/
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