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Chemical additives enable native mass spectrometry measurement of membrane protein oligomeric state within intact nanodiscs
Membrane proteins play critical biochemical roles but remain challenging to study. Recently, native or nondenaturing mass spectrometry (MS) has made great strides in characterizing membrane protein interactions. However, conventional native MS relies on detergent micelles, which may disrupt natural...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6475481/ https://ncbi.nlm.nih.gov/pubmed/30586296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11529 |
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