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Measuring Remodeling of the Lipid Environment Surrounding Membrane Proteins with Lipid Exchange and Native Mass Spectrometry

Due to their crucial biochemical roles, membrane proteins are important drug targets. Although it is clear that lipids can influence membrane protein function, the chemistry of lipid binding remains difficult to study because protein-lipid interactions are polydisperse, competitive, and transient. F...

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Vydáno v:Anal Chem
Hlavní autoři: Zhang, Guozhi, Keener, James E., Marty, Michael T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204402/
https://ncbi.nlm.nih.gov/pubmed/32250609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00786
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