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Measuring Remodeling of the Lipid Environment Surrounding Membrane Proteins with Lipid Exchange and Native Mass Spectrometry

Due to their crucial biochemical roles, membrane proteins are important drug targets. Although it is clear that lipids can influence membrane protein function, the chemistry of lipid binding remains difficult to study because protein-lipid interactions are polydisperse, competitive, and transient. F...

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Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Zhang, Guozhi, Keener, James E., Marty, Michael T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204402/
https://ncbi.nlm.nih.gov/pubmed/32250609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00786
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