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Native Mass Spectrometry Characterizes Intact Nanodisc Lipoprotein Complexes

We describe here the analysis of Nanodisc complexes by using native mass spectrometry (MS) to characterize their molecular weight (MW) and polydispersity. Nanodiscs are nanoscale lipid bilayers that offer a platform for solubilizing membrane proteins. Unlike detergent micelles, Nanodiscs are native-...

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Bibliografski detalji
Glavni autori: Marty, Michael T., Zhang, Hao, Cui, Weidong, Blankenship, Robert E., Gross, Michael L., Sligar, Stephen G.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536499/
https://ncbi.nlm.nih.gov/pubmed/23061736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac302663f
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