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Native Mass Spectrometry of Antimicrobial Peptides in Lipid Nanodiscs Elucidates Complex Assembly

Antimicrobial peptides (AMPs) are generally cationic and amphipathic peptides that show potential applications to combat the growing threat of antibiotic resistant infections. AMPs are known to interact with bacterial membranes, but their mechanisms of toxicity and selectivity are poorly understood,...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Walker, Lawrence R., Marzluff, Elaine M., Townsend, Julia A., Resager, William C., Marty, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635019/
https://ncbi.nlm.nih.gov/pubmed/31251560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b02261
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