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Native Mass Spectrometry of Antimicrobial Peptides in Lipid Nanodiscs Elucidates Complex Assembly

Antimicrobial peptides (AMPs) are generally cationic and amphipathic peptides that show potential applications to combat the growing threat of antibiotic resistant infections. AMPs are known to interact with bacterial membranes, but their mechanisms of toxicity and selectivity are poorly understood,...

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Détails bibliographiques
Publié dans:Anal Chem
Auteurs principaux: Walker, Lawrence R., Marzluff, Elaine M., Townsend, Julia A., Resager, William C., Marty, Michael T.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635019/
https://ncbi.nlm.nih.gov/pubmed/31251560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b02261
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