Parent-of-origin differences in DNA methylation of X chromosome genes in T lymphocytes

Many autoimmune diseases are more frequent in females than in males in humans and their mouse models, and sex differences in immune responses have been shown. Despite extensive studies of sex hormones, mechanisms underlying these sex differences remain unclear. Here, we focused on sex chromosomes us...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Golden, Lisa C., Itoh, Yuichiro, Itoh, Noriko, Iyengar, Sonia, Coit, Patrick, Salama, Youstina, Arnold, Arthur P., Sawalha, Amr H., Voskuhl, Rhonda R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936674/
https://ncbi.nlm.nih.gov/pubmed/31822606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910072116
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