Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis

Regional differences in neurons, astrocytes, oligodendrocytes, and microglia exist in the brain during health, and regional differences in the transcriptome may occur for each cell type during neurodegeneration. Multiple sclerosis (MS) is multifocal, and regional differences in the astrocyte transcr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Voskuhl, Rhonda R., Itoh, Noriko, Tassoni, Alessia, Matsukawa, Macy Akiyo, Ren, Emily, Tse, Vincent, Jang, Ellis, Suen, Timothy Takazo, Itoh, Yuichiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525478/
https://ncbi.nlm.nih.gov/pubmed/31040210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821306116
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