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The X-linked histone demethylase Kdm6a in CD4(+) T lymphocytes modulates autoimmunity

Multiple sclerosis (MS) is a putative T cell–mediated autoimmune disease. As with many autoimmune diseases, females are more susceptible than males. Sexual dimorphisms may be due to differences in sex hormones, sex chromosomes, or both. Regarding sex chromosome genes, a small percentage of X chromos...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Itoh, Yuichiro, Golden, Lisa C., Itoh, Noriko, Matsukawa, Macy Akiyo, Ren, Emily, Tse, Vincent, Arnold, Arthur P., Voskuhl, Rhonda R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715385/
https://ncbi.nlm.nih.gov/pubmed/31403472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126250
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