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XY sex chromosome complement, compared with XX, in the CNS confers greater neurodegeneration during experimental autoimmune encephalomyelitis

Women are more susceptible to multiple sclerosis (MS) and have more robust immune responses than men. However, men with MS tend to demonstrate a more progressive disease course than women, suggesting a disconnect between the severity of an immune attack and the CNS response to a given immune attack....

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Hlavní autoři: Du, Sienmi, Itoh, Noriko, Askarinam, Sahar, Hill, Haley, Arnold, Arthur P., Voskuhl, Rhonda R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932937/
https://ncbi.nlm.nih.gov/pubmed/24550311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307091111
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