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The XX Sex Chromosome Complement in Mice is Associated with Increased Spontaneous Lupus as compared to XY
OBJECTIVES: Many autoimmune diseases are characterized by a female predominance. This may be caused by sex hormones, sex chromosomes or both. Here, we use a transgenic mouse model to investigate how sex chromosome complement, not confounded by differences in gonadal type, might contribute to lupus p...
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| Publicado no: | Ann Rheum Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452281/ https://ncbi.nlm.nih.gov/pubmed/22580585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-201246 |
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