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The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila

Regulated gene expression is necessary for developmental and homeostatic processes. The KDM5 family of transcriptional regulators are histone H3 lysine 4 demethylases that can function through both demethylase-dependent and -independent mechanisms. While loss and overexpression of KDM5 proteins are...

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Pubblicato in:Genetics
Autori principali: Drelon, Coralie, Belalcazar, Helen M., Secombe, Julie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028249/
https://ncbi.nlm.nih.gov/pubmed/29764901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301004
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