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The histone demethylase KDM5 activates gene expression by recognizing chromatin context through its PHD reader motif
KDM5 family proteins are critically important transcriptional regulators whose physiological functions in the context of a whole animal remain largely unknown. Using genome-wide gene expression and binding analyses in Drosophila adults, we demonstrate that KDM5 (Lid) is a direct regulator of genes r...
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Publicado no: | Cell Rep |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684901/ https://ncbi.nlm.nih.gov/pubmed/26673323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.007 |
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