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The histone demethylase KDM5 activates gene expression by recognizing chromatin context through its PHD reader motif

KDM5 family proteins are critically important transcriptional regulators whose physiological functions in the context of a whole animal remain largely unknown. Using genome-wide gene expression and binding analyses in Drosophila adults, we demonstrate that KDM5 (Lid) is a direct regulator of genes r...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Liu, Xingyin, Secombe, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684901/
https://ncbi.nlm.nih.gov/pubmed/26673323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.007
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