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The histone demethylase KDM5 activates gene expression by recognizing chromatin context through its PHD reader motif

KDM5 family proteins are critically important transcriptional regulators whose physiological functions in the context of a whole animal remain largely unknown. Using genome-wide gene expression and binding analyses in Drosophila adults, we demonstrate that KDM5 (Lid) is a direct regulator of genes r...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Liu, Xingyin, Secombe, Julie
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684901/
https://ncbi.nlm.nih.gov/pubmed/26673323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.007
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