Drosophila Histone Demethylase KDM5 regulates social behavior through immune control and gut microbiota maintanence

Loss of function mutations in the histone demethylase KDM5A, KDM5B or KDM5C are found in intellectual disability (ID) and autism spectrum disorders (ASD) patients. Here, we use the model organism Drosophila melanogaster to delineate how KDM5 contributes to ID and ASD. We show that reducing of KDM5 c...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Chen, Kun, Luan, Xiaoting, Liu, Qisha, Wang, Jianwei, Chang, Xinxia, Snijders, Antoine M., Mao, Jian-Hua, Secombe, Julie, Dan, Zhou, Chen, Jian-Huan, Wang, Zibin, Dong, Xiao, Qiu, Chen, Chang, Xiaoai, Zhang, Dong, Celniker, Susan E., Liu, Xingyin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749836/
https://ncbi.nlm.nih.gov/pubmed/30902578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.02.003
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