Drosophila Histone Demethylase KDM5 regulates social behavior through immune control and gut microbiota maintanence

Loss of function mutations in the histone demethylase KDM5A, KDM5B or KDM5C are found in intellectual disability (ID) and autism spectrum disorders (ASD) patients. Here, we use the model organism Drosophila melanogaster to delineate how KDM5 contributes to ID and ASD. We show that reducing of KDM5 c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Host Microbe
मुख्य लेखकों: Chen, Kun, Luan, Xiaoting, Liu, Qisha, Wang, Jianwei, Chang, Xinxia, Snijders, Antoine M., Mao, Jian-Hua, Secombe, Julie, Dan, Zhou, Chen, Jian-Huan, Wang, Zibin, Dong, Xiao, Qiu, Chen, Chang, Xiaoai, Zhang, Dong, Celniker, Susan E., Liu, Xingyin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749836/
https://ncbi.nlm.nih.gov/pubmed/30902578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.02.003
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