Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH

Non-alcoholic steatohepatitis (NASH) is a common chronic liver disorder in developed countries, with the associated clinical complications driven by portal hypertension (PH). PH may precede fibrosis development, probably due to endothelial dysfunction at early stages of the disease. Our aim was to c...

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Pubblicato in:Sci Rep
Autori principali: Bravo, Miren, Raurell, Imma, Hide, Diana, Fernández-Iglesias, Anabel, Gil, Mar, Barberá, Aurora, Salcedo, Maria Teresa, Augustin, Salvador, Genescà, Joan, Martell, María
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934751/
https://ncbi.nlm.nih.gov/pubmed/31882668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56366-2
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