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Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH

Non-alcoholic steatohepatitis (NASH) is a common chronic liver disorder in developed countries, with the associated clinical complications driven by portal hypertension (PH). PH may precede fibrosis development, probably due to endothelial dysfunction at early stages of the disease. Our aim was to c...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Bravo, Miren, Raurell, Imma, Hide, Diana, Fernández-Iglesias, Anabel, Gil, Mar, Barberá, Aurora, Salcedo, Maria Teresa, Augustin, Salvador, Genescà, Joan, Martell, María
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934751/
https://ncbi.nlm.nih.gov/pubmed/31882668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56366-2
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