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A Nitric Oxide-Donating Statin Decreases Portal Pressure with a Better Toxicity Profile than Conventional Statins in Cirrhotic Rats

Statins present many beneficial effects in chronic liver disease, but concerns about safety exist. We evaluated the hepatic effects of a nitric oxide-releasing atorvastatin (NCX 6560) compared to conventional statins. Simvastatin, atorvastatin and NCX 6560 were evaluated in four-week bile duct-ligat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Rodríguez, Sarai, Raurell, Imma, Torres-Arauz, Manuel, García-Lezana, Teresa, Genescà, Joan, Martell, María
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233977/
https://ncbi.nlm.nih.gov/pubmed/28084470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40461
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