Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH

Non-alcoholic steatohepatitis (NASH) is a common chronic liver disorder in developed countries, with the associated clinical complications driven by portal hypertension (PH). PH may precede fibrosis development, probably due to endothelial dysfunction at early stages of the disease. Our aim was to c...

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Опубликовано в: :Sci Rep
Главные авторы: Bravo, Miren, Raurell, Imma, Hide, Diana, Fernández-Iglesias, Anabel, Gil, Mar, Barberá, Aurora, Salcedo, Maria Teresa, Augustin, Salvador, Genescà, Joan, Martell, María
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934751/
https://ncbi.nlm.nih.gov/pubmed/31882668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56366-2
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