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Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH

Non-alcoholic steatohepatitis (NASH) is a common chronic liver disorder in developed countries, with the associated clinical complications driven by portal hypertension (PH). PH may precede fibrosis development, probably due to endothelial dysfunction at early stages of the disease. Our aim was to c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bravo, Miren, Raurell, Imma, Hide, Diana, Fernández-Iglesias, Anabel, Gil, Mar, Barberá, Aurora, Salcedo, Maria Teresa, Augustin, Salvador, Genescà, Joan, Martell, María
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934751/
https://ncbi.nlm.nih.gov/pubmed/31882668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56366-2
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