Experimental arthritis and Porphyromonas gingivalis administration synergistically decrease bone regeneration in femoral cortical defects

Porphyromonas gingivalis infection can lead to periodontitis and dysbiosis, which are known risk factors for rheumatoid arthritis (RA). We investigated whether P. gingivalis administration affected bone regeneration in mice with or without arthritis. We administered P. gingivalis to male DBA/1 J mic...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Okumura, Go, Kondo, Naoki, Sato, Keisuke, Yamazaki, Kazuhisa, Ohshima, Hayato, Kawashima, Hiroyuki, Ogose, Akira, Endo, Naoto
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934576/
https://ncbi.nlm.nih.gov/pubmed/31882624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56265-6
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