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The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3
BACKGROUND AND AIM: The pathophysiology of rheumatoid arthritis (RA) is characterized by excess production of pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6) by neutrophils and macrophages in synovium. Additionally, these cytoki...
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| Gepubliceerd in: | J Orthop Surg Res |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7371465/ https://ncbi.nlm.nih.gov/pubmed/32131874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-020-01595-9 |
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