Experimental arthritis and Porphyromonas gingivalis administration synergistically decrease bone regeneration in femoral cortical defects

Porphyromonas gingivalis infection can lead to periodontitis and dysbiosis, which are known risk factors for rheumatoid arthritis (RA). We investigated whether P. gingivalis administration affected bone regeneration in mice with or without arthritis. We administered P. gingivalis to male DBA/1 J mic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Okumura, Go, Kondo, Naoki, Sato, Keisuke, Yamazaki, Kazuhisa, Ohshima, Hayato, Kawashima, Hiroyuki, Ogose, Akira, Endo, Naoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934576/
https://ncbi.nlm.nih.gov/pubmed/31882624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56265-6
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