Indirect regulation of PCSK9 gene in inflammatory response by Porphyromonas gingivalis infection

Pro-protein convertase subtilisin/kexin type 9 (PCSK9), a secreted serine protease, regulates serum low-density lipoprotein (LDL) cholesterol levels by targeting the degradation of LDL receptor (LDLR) in the liver. Although previous reports describe elevated levels of PCSK9 in patients with periodon...

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Bibliographische Detailangaben
Veröffentlicht in:Heliyon
Hauptverfasser: Yokoji-Takeuchi, Mai, Tabeta, Koichi, Takahashi, Naoki, Arimatsu, Kei, Miyazawa, Haruna, Matsuda-Matsukawa, Yumi, Sato, Keisuke, Yamada, Miki, Yamazaki, Kazuhisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328067/
https://ncbi.nlm.nih.gov/pubmed/30671557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e01111
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