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Molecular structures of the human Slo1 K(+) channel in complex with β4

Slo1 is a Ca(2+)- and voltage-activated K(+) channel that underlies skeletal and smooth muscle contraction, audition, hormone secretion and neurotransmitter release. In mammals, Slo1 is regulated by auxiliary proteins that confer tissue-specific gating and pharmacological properties. This study pres...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Tao, Xiao, MacKinnon, Roderick
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934384/
https://ncbi.nlm.nih.gov/pubmed/31815672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51409
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