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Metabolism of Histone Deacetylase Proteins Opsonizes Tumor Cells to Checkpoint Inhibitory Immunotherapies

LC3-associated phagocytosis, a distinct form of autophagy, plays a key role in antigen presentation. Autophagy itself plays a central role in the regulation of cellular metabolism. Proteins that regulate autophagy include the AMPK which senses high levels of AMP, and mTOR, which integrates amino aci...

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Détails bibliographiques
Publié dans:Immunometabolism
Auteurs principaux: Dent, Paul, Booth, Laurence, Poklepovic, Andrew
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934083/
https://ncbi.nlm.nih.gov/pubmed/31885880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20200002
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