Characterization and modulation of microglial phenotypes in an animal model of severe sepsis

We aim to characterize the kinetics of early and late microglial phenotypes after systemic inflammation in an animal model of severe sepsis and the effects of minocycline on these phenotypes. Rats were subjected to CLP, and some animals were treated with minocycline (10 ug/kg) by i.c.v. administrati...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Michels, Monique, Abatti, Mariane Rocha, Ávila, Pricila, Vieira, Andriele, Borges, Heloisa, Carvalho Junior, Celso, Wendhausen, Diogo, Gasparotto, Juciano, Tiefensee Ribeiro, Camila, Moreira, José Claudio Fonseca, Gelain, Daniel Pens, Dal‐Pizzol, Felipe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933367/
https://ncbi.nlm.nih.gov/pubmed/31654493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14606
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