Characterization and modulation of microglial phenotypes in an animal model of severe sepsis

We aim to characterize the kinetics of early and late microglial phenotypes after systemic inflammation in an animal model of severe sepsis and the effects of minocycline on these phenotypes. Rats were subjected to CLP, and some animals were treated with minocycline (10 ug/kg) by i.c.v. administrati...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Michels, Monique, Abatti, Mariane Rocha, Ávila, Pricila, Vieira, Andriele, Borges, Heloisa, Carvalho Junior, Celso, Wendhausen, Diogo, Gasparotto, Juciano, Tiefensee Ribeiro, Camila, Moreira, José Claudio Fonseca, Gelain, Daniel Pens, Dal‐Pizzol, Felipe
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933367/
https://ncbi.nlm.nih.gov/pubmed/31654493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14606
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