Characterization and modulation of microglial phenotypes in an animal model of severe sepsis

We aim to characterize the kinetics of early and late microglial phenotypes after systemic inflammation in an animal model of severe sepsis and the effects of minocycline on these phenotypes. Rats were subjected to CLP, and some animals were treated with minocycline (10 ug/kg) by i.c.v. administrati...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Michels, Monique, Abatti, Mariane Rocha, Ávila, Pricila, Vieira, Andriele, Borges, Heloisa, Carvalho Junior, Celso, Wendhausen, Diogo, Gasparotto, Juciano, Tiefensee Ribeiro, Camila, Moreira, José Claudio Fonseca, Gelain, Daniel Pens, Dal‐Pizzol, Felipe
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933367/
https://ncbi.nlm.nih.gov/pubmed/31654493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14606
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